Skip to main content
What is the genotype and phenotype variation in humans? Here is a study to sort it out:

The aim of the 1000 Genomes Project is to discover, genotype and provide accurate haplotype information on all forms of human DNA polymorphism in multiple human populations. Specifically, the goal is to characterize over 95% of variants that are in genomic regions accessible to current high-throughput sequencing technologies and that have allele frequency of 1% or higher (the classical definition of polymorphism) in each of five major population groups (populations in or with ancestry from Europe, East Asia, South Asia, West Africa and the Americas). Because functional alleles are often found in coding regions and have reduced allele frequencies, lower frequency alleles (down towards 0.1%) will also be catalogued in such regions.

http://www.nature.com/nature/journal/v467/n7319/full/nature09534.html

Comments

Popular posts from this blog

Nwahulwana

Wazimbo's "Nwahulwana" Found this on a German site: Warum wanderst du von Bar zu Bar? (“Why do you wander from bar to bar?”) So, the first time I heard this I thought I recognized some Portuguese, but it’s illusory; the language is actually Ronga. I suppose it was just the echoes of Brazilian music. I found, though, a translation into Portuguese, which I will translate to English, but here’s the thing: this transcription of the words isn’t correct. Also, I’m almost certain I hear “vôce” which means “you” in the lyrics. First, “nwahulwana” itself is a soft expression for prostitute, hence “night bird” is the poetic meaning. I thought it was a love song. My wife thought it was a prayer (probably because of the way Wazimbo lifts his eyes to the sky when he sings “Maria”). So, it is something like this, but there are mistakes, because the lines don’t match up. Also, I wonder if he is singing “Nwahulwana” when the song starts - . It’s hard to know since I don’t

My review of The Handmaid's Tale

The Handmaid's Tale by Margaret Atwood My rating: 5 of 5 stars Margaret Atwood’s The Handmaid’s Tale is brilliant literary science fiction. I will discuss the literary aspects of it in a moment, but first it’s important to place it squarely in the domain of science fiction. First, under Darko Suvin's definition of sci fi, the question is whether there is cognitive strangeness and nova. They are very apparent, specifically the new assignment of gender roles, along with the reason they exist. The nova introduced are ecological disasters, an enormous rise in failure to Gileadeans to sexually reproduce, and the imposition of a fundamentalist government that divides women by their function, entirely controlling them. We know (again from the lecture) that Atwood was responding to societal changes, such as the rise of the Moral Majority, which lends a spooky plausibility to the strangeness, making it not so strange and that much scarier. Delany's definition is wider. He as

Script Abbreviations in Screen Writing

SCRIPT ABBREVIATIONS  ELS extreme long shot  MLS medium long shot  LS long shot  MS medium shot  MCU medium close-up  CU close-up  ECU extreme close-up  OS over-the-shoulder shot  2-S or 3-S two-shot or three-shot  POV point of view shot  ZI or ZO zoom in or zoom out  INT interior  EXT exterior  SOT or SOF sound on tape or sound on film BG background  SFX or F/X special effects (can be either sound or visual)  VO voice-over  OSV off-screen voice  DIS dissolve  MIC microphone  VTR videotape  Q cue (as in cue talent)  ANNCR announcer  SUPER superimposition